Обмен магния очень важная тема.
Здесь все давно изучено. Набираем в PubMed:
http://www.ncbi.nlm.nih.gov/sites/entrez
‘Magnesium’, получается 3939 ссылок.
Вот самые свежие.
Nutr Cancer. 2009;61(1):131-6.
Magnesium deficiency affects mammary epithelial cell proliferation: involvement of oxidative stress.
Wolf FI, Trapani V, Simonacci M, Boninsegna A, Mazur A, Maier JA.
Istituto di Patologia Generale, e Centro di Ricerche Oncologiche Giovanni XXIII, Facoltа di Medicina, Universitа Cattolica del Sacro Cuore, Rome, Italy.
fwolf@rm.unicatt.it
Low Mg availability reversibly inhibited the growth of mammary epithelial HC11 cells by increasing the number of cells in the G0/G1 phase of the cell cycle. Because low Mg has been reported to promote oxidative reactions, we considered that low Mg-dependent growth arrest was mediated by oxidative stress. Surprisingly, both dichlorofluorescein-detectable reactive oxygen species and hydrogen peroxide-induced oxidative DNA damage were found to be lower in cells cultured in low Mg than in cells grown under control or high-Mg conditions. Gene expression profiling of low- and high-Mg cells showed the modulation of several genes, some regulating cell proliferation. In addition, low Mg cells also displayed overexpression of glutathione S-transferase (GST), leading to increased enzymatic activity. Of note, GST has been shown to modulate cell growth; therefore, we suggest that in low-Mg cells, GST upregulation might have a dual role in protecting against oxidative stress and in modulating cell proliferation.
http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum
J Hum Hypertens. 2008 Nov 20.
The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
Guerrero-Romero F, Rodrнguez-Morбn M.
1Biomedical Research Unit of the Mexican Social Security Institute, Research Group on Diabetes and Chronic Illnesses, and Nucleus of Research and Clinical Diagnosis (NIDIAC), Durango, Mexico.
To test the blood pressure (BP)-lowering effect of oral magnesium supplementation (that is, magnesium chloride (MgCl(2)) solution) in diabetic hypertensive adults with hypomagnesaemia not on diuretic treatment but receiving concurrent captopril, we conducted a double-blind, placebo-controlled trial. Eighty-two subjects between 40 and 75 years of age were randomly enrolled. Over 4 months, subjects in the intervention group received 2.5 g of MgCl(2) (50 ml of a solution containing 50 g of MgCl(2) per 1000 ml of solution) equivalent to 450 mg of elemental magnesium, and control subjects inert placebo. The primary trial end point was a reduction in systolic (SBP) and diastolic (DBP) blood pressure. Complete follow-up was achieved for 79 of the 82 randomized subjects. SBP (-20.4+/-15.9 versus -4.7 +/- 12.7 mm Hg, P=0.03) and DBP (-8.7+/-16.3 versus -1.2+/-12.6 mm Hg, P=0.02) showed significant decreases, and high-density lipoprotein-cholesterol (0.1+/-0.6 versus -0.1+/-0.7 mmol l(-1), P=0.04) a significant increase in the magnesium group compared to the placebo group. The adjusted odds ratio between serum magnesium and BP was 2.8 (95%CI: 1.4-6.9). Oral magnesium supplementation with MgCl(2) significantly reduces SBP and DBP in diabetic hypertensive adults with hypomagnesaemia. Journal of Human Hypertension advance online publication, 20 November 2008; doi:10.1038/jhh.2008.129.
http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum
Пытливые умы, после изучения мировой научной мысли, смогут решить стоит ли принимать участие в химических опытах.
Если будут желающие переводить с английского, я приготовлю литературный обзор.
Цитата:
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Сообщение от Ksenik
Или есть какой-то специальный анализ?
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По одному анализу крови оценить обмен какого-то ни было микроэлемента не возможно.
Микроэлементы исследуются одновременно во всех доступных биосредах: крови, моче, ногтях, волосах.
О лаборатории, которая проводит все эти исследования я уже писал.